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新規RGD含有ペプチドおよび象牙質再生剤、骨再生剤、歯周組織再生剤
专利权人:
学校法人東日本学園
发明人:
安田 善之,斎藤 隆史
申请号:
JP2008144109
公开号:
JP5519121B2
申请日:
2008.06.02
申请国别(地区):
JP
年份:
2014
代理人:
摘要:

PROBLEM TO BE SOLVED: To provide a new peptide synthesizable artificially and having bone regenerative effect.

SOLUTION: The new peptide has either one of the following amino acid sequences: SESDNNSSSRGDASYNSDES (1-1), ESDNNSSSRGDASYNSDES (1-2), SDNNSSSRGDASYNSDES (1-3), SESDNNSSSRGDASYNSDE (1-4), SESDNNSSSRGDASYNSD (1-5), SESDNNSSSRGDASYNS (1-6), SESDNNSSSRGDASYN (1-7), ANSESDNNSSSRGDA (2-1), NSESDNNSSSRGDA (2-2), SRGDASYNSDESKD (3-1), SRGDASYNSDESK (3-2), and DNNSSSRGDASYNSD (4). A dentine regenerative agent, a bone regenerative agent and a periodontal tissue regenerative agent each comprising the above peptide are also provided. The dentine regenerative agent, the bone regenerative agent and the periodontal tissue regenerative agent may include, in addition, porous hydroxyapatite or I-type collagens recombinant form, respectively.

COPYRIGHT: (C)2010,JPO&INPIT

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