The present invention relates to a composition for prevention and treatment of ischemic retinopathy comprising transferrin as an active ingredient, and the composition for preventing and treating ischemic retinopathy according to the present invention is a composition for preventing and treating ischemic retinopathy by preventing retinal ganglion cell apoptosis, And is useful for prevention and treatment of ischemic retinopathy.본 발명은 트랜스페린을 유효성분으로 함유하는 허혈성망막병증 예방 및 치료용 조성물에 관한 것으로, 본 발명에 따른 허혈성망막병증 예방 및 치료용 조성물은 망막신경절세포의 세포사멸을 방지하여 허혈성망막병증을 예방 및 치료하는 효과가 탁월하여, 허혈성망막병증 예방 및 치료에 유용하다.