Jiangsu Hengrui Medicine Co. Ltd.;Shanghai Hengrui Pharmaceutical Co., Ltd
发明人:
申请号:
EP18809419.7
公开号:
EP3632932A1
申请日:
2018.05.31
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Provided are an anti-CD40 antibody, an antigen binding fragment thereof, and a medical use thereof. Also provided are a chimeric antibody and a humanized antibody including a CDR region of the anti-CD40 antibody, a pharmaceutical composition including the human anti-CD40 antibody and the antigen binding fragment thereof, and an application thereof as an anti-cancer drug. In particular, provided are a humanized anti-CD40 antibody, and an application thereof in preparation of a drug to treat a CD40-mediated disease or disorder.