PROBLEM TO BE SOLVED: To provide an enzyme-containing cleanser composition for endoscope-cleansing machines, little in foaming even at low temperature and excellent in cleansing force, and to provide a method for cleansing an endoscope.SOLUTION: The enzyme-containing cleanser composition for the endoscope-cleansing machines contains (A) 1-50 mass% of a surfactant and (B) a protease (hereinafter referred to as a component (B)), wherein, the rate of a non-ionic surfactant represented by general formula (I) below in the surfactant is &ge90 mass%: R-O-[(EO)/(PO)]-H (I), wherein R is 7-9C branched alkyl EO is ethanediyloxy PO is propanediyloxy m and n are average addition molar numbers m is a number of 1-30 n is a number of 2-50 "/" is a symbol showing that EO and PO may be random or block the addition order of EO and PO is not asked.
