A medicine container configured to hold one or more different medications. The container may include an orientation sensor to determine the orientation of the container. The container may also include one or more additional sensors to detect other physical characteristics about the container and/or medicine. The orientation of the container in combination with the information from the one or more additional sensors is used to determine an accurate indication of an amount of the medicine within the container and thus usage information. The container also includes a wireless transmitter for transmitting the information regarding the medicine to a remote location.