In a method and apparatus for adjusting a table position in a medical data acquisition scanner, image data relating to a body region are generated by operation of the medical data acquisition scanner by running a scanning protocol. The scanning protocol is intended to be used independently of the body region that is mapped. An iso-mode, in which a relative position of the body region relative to the isocenter of the medical data acquisition scanner can be set via the table position in accordance with an optimization criterion, and on a ref-mode, in which the table position is set at a predetermined reference position, are provided. A mode of operation is selected from the iso-mode and the ref-mode as dependent on anatomical information relating to the body region and/or a relative position of the body region relative to the isocenter that ensues in the reference position, and before the running of and/or during the running of the selected scanning protocol, the table position is set according to the selected mode of operation.