Christophe Moinet,Marc Courchesne,Liliane Halab,Nathalie Chauret,Laval Chan Chun Kong
申请号:
US12830294
公开号:
US08431556B2
申请日:
2010.07.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention relates to 21-keto triterpene compounds of formula (I):wherein R1, X and Y are as defined herein, and pharmaceutically acceptable salts and solvates thereof. These compounds exhibit significant anti-HIV activity. Thus, the invention also relates to methods for prevention or treatment of HIV infections by administering therapeutically effective amounts of a compound of formula (I), or a pharmaceutically acceptable salt or solvate thereof to a subject in need of such treatment.