Chimeric antigen receptor (CAR) with antigen binding domains to the T cell receptor beta constant region

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专利权人:

UCL Business PLC

发明人:

Pule, Martin,Maciocia, Paul

申请号：

AU2015225944

公开号：

AU2015225944B2

申请日:

2015.03.05

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

The present disclosure relates to a chimeric antigen receptor (CAR) which comprises an antigen-binding domain which selectively binds TCR beta constant region 1 (TRBC1) or TRBC2； cells； such a T cells comprising such a CAR； and the use of such cells for the treatment of a T-cell lymphoma or leukaemia in a subject.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/