KIM, HYUNG SEO,김형서,CHOI, YOUNG KEUN,최영근,CHO, JUNG HYUN,조정현,KIM, JIN CHEUL,김진철,KIM, YONG IL,김용일,PARK, JAE HYUN,박재현,WOO, JONG SOO,우종수,KIM, HYUNG SEOKR,CHOI, YOUNG KEUNKR,CHO, JUNG HYUNKR,KIM, JIN CHEULKR,KIM, YONG ILKR,PARK, JAE HYUNKR,WOO, JONG SOOKR
申请号：
KR1020150023152
公开号：
KR1020160100570A
申请日:
2015.02.16
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
The present invention relates to a pharmaceutical oral preparation including tamsulosin hydrochloride-containing sustained release granule. More specifically, provided is a pharmaceutical oral preparation and a production method thereof. According to the present invention, the sustained release granule contains: 10-300 parts by weight of polyvinyl acetate, 5-250 parts by weight of hydroxypropyl methylcellulose, and 1-450 parts by weight of a diluent, with respect to 1 part by weight of tamsulosin hydrochloride, wherein the weight ratio of the sustained release granule is 360-495 parts by weight based on 1 part by weight of tamsulosin hydrochloride.본 발명은 탐수로신 염산염 함유 서방성 과립을 포함하는 경구용 약제학적 제제로서, 상기 서방성 과립은 탐수로신 염산염 1 중량부에 대해, 폴리비닐아세테이트 10 ~ 300 중량부, 히드록시프로필메틸셀룰로오스 5 ~ 250 중량부, 및 희석제 1 ~ 450 중량부를 포함하고, 상기 서방성 과립은 탐수로신 염산염 1 중량부에 대해 360 ~ 495 중량부의 중량비를 갖는 것인 경구용 약제학적 제제 및 그 제조방법을 제공한다.
