Stephanie A. Kramer;Wenbin Lin;Demin Liu;Joseph Della Rocca;Christopher Y. Poon
发明人:
Wenbin Lin,Demin Liu,Joseph Della Rocca,Stephanie A. Kramer,Christopher Y. Poon
申请号:
US14131575
公开号:
US20140234210A1
申请日:
2012.07.09
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate nanoparticles and materials comprising the nanoparticles, and methods of using the compositions to treat cancer or bone-related disorders (e.g., bone-resorption-related diseases, osteoporosis, Paget's disease, and bone metastases) and as imaging agents.