Sam Kattar;David Guerin;Yunfeng Bai;Jianmin FU;Mark E. Scott;Normon Kong;Christopher Dinsmore;Danielle Molinari;Yumei Liu;Zhixiang Zheng;Peter Fuller
发明人:
Mark E. Scott,David Guerin,Danielle Molinari,Sam Kattar,Peter Fuller,Christopher Dinsmore,Normon Kong,Yunfeng Bai,Jianmin FU,Yumei Liu,Zhixiang Zheng
申请号:
US15519740
公开号:
US20170240567A1
申请日:
2015.10.21
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The instant invention provides compounds of Formula (I) which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer. The present invention provides novel compounds which are inhibitors of JAKs. The invention also provides a method for the treatment and prevention of JAK-mediated diseases and disorders using the novel compounds, as well as pharmaceutical compositions containing the compounds.