Walter J. Koch,Patrick Most,Sven T. Pleger,Joseph E. Rabinowitz
申请号：
US12447558
公开号：
US08383601B2
申请日:
2007.10.30
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention provides nucleic acid segments, compositions and methods for the treatment of heart failure, vascular dysfunction, endothelial dysfunction, diabetes, [Ca2+]i regulation and NO synthase dysfunction. Adeno-associated and adenovirus are used as gene delivery vectors for the nucleic acid segments to product long term over-expression of S100A1, a small calcium sensing protein associated with the disclosed ailments and dysfunctions.
