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SOLID DISPERSION WITH IMPROVED SOLUBILITY COMPRISING TETRAZOLE DERIVATIVE AS AN ACTIVE INGREDIENT
专利权人:
发明人:
Yong Il Kim,Jun Young Choi,Young Keun Choi,Jae Hyun Park,Jong Soo Woo
申请号:
US14439735
公开号:
US20150272943A1
申请日:
2013.12.12
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to an amorphous solid dispersion comprising a tetrazole derivative of the formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient. The solid dispersion of the present invention comprises a water-soluble polymer or an acid so as to improve the solubility of its active ingredient, i.e., the tetrazole derivative of the formula (I), thereby improving its absorption rate, and thus can be effectively used to reduce multi-drug resistance (MDR) in cancer cells
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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