DERIVES D'IMIDAZOTHIADIAZOLE ET D'IMIDAZOPYRIDAZINE UTILES COMME INHIBITEURS DES RECEPTEURS 4 ACTIVES PAR LES PROTEASES (PAR4) POUR TRAITER L'AGREGATION PLAQUETTAIRE
UNIVERSITE DE MONTREAL;BRISTOL-MYERS SQUIBB COMPANY
发明人:
BANVILLE, JACQUES,REMILLARD, ROGER,RUEDIGER, EDWARD H.,DEON, DANIEL H.,GAGNON, MARC,DUBE, LAURENCE,GUY, JULIA,PRIESTLEY, ELDON SCOTT,POSY, SHOSHANA L.,MAXWELL, BRAD D.,WONG, PANCRAS C.
申请号：
CA2871650
公开号：
CA2871650A1
申请日:
2013.04.24
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention provides thiazole compounds of Formula I wherein W, Y, R0, R2, R4, R5, R6, R7, X1, X2, X3 and X4 are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments for treating or preventing thromboembolic disorders.
