WANG, ZHAOLIN,YE, PING,RICARDO, ALONSO,JOSEPHSON, KRISTOPHER,ANDERSON, PAUL,ARATA, MICHELLE DENISE,MA, ZHONG,NIMS, NATHAN EZEKIEL,SCHNEIDER, EBERHARD,SCHURMANN, GREGOR,WAGNER, PETER,TRECO, DOUGLAS A.
申请号：
CA2873511
公开号：
CA2873511A1
申请日:
2013.03.14
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention provides inhibitors and/or antagonists of plasma kallikrein. Also provided are methods of utilizing the inhibitors as therapeutics and provides for the production of peptides and peptide mimetics having improved pharmacokinetic and pharmacodynamic properties for inhibiting plasma kallikrein and their use in the treatment of diseases where reductions in circulating plasma kallikrein activity may be therapeutically beneficial.
