This invention relates to wettable biomedical devices comprising amphiphilic block copolymers. The amphiphilic block copolymers are useful as internal wetting agents for biomedical applications, such as implantable devices, ophthalmic devices and in one embodiment, contact lenses.本發明係有關於包含兩性嵌段共聚物之可溼潤的生醫裝置,此兩性嵌段共聚物可於生醫應用上,例如:可植入之裝置、眼睛的裝置、以及於一實例中為隱形眼鏡,用作內部溼潤劑。