Systems and methods are described for splitting DICOM medical image series into framesets. In one implementation, a method of splitting a DICOM medical image series into framesets includes determining that a first DICOM image object of the DICOM medical image series is the first DICOM object of the medical image series and creating a first frame set including the first DICOM image object in response to determining that the first DICOM image object is the first DICOM object of the medical image series. In subsequent steps, the method may include determining that a second DICOM image object of the DICOM medical image series does not have more than one image frame； and determining whether a first predefined DICOM tag of interest of the second DICOM image object matches a first DICOM tag of interest of a first image of the first frameset.
