ANTIBODIES SPECIFIC FOR MMP1/HLA-A2 COMPLEX

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专利权人:

发明人:

申请号：

EP17158565.6

公开号：

EP3366704A1

申请日:

2017.02.28

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The invention provides multispecific antigen-binding molecules having a specificity for a complex of matrix metallopeptidase 1 (MMP1) and the human leukocyte antigen A2 (HLA-A2), and a further specificity for engaging an immune effector cell, such as a T-cell via CD3 receptor or a NK-cell via CD16A receptor. The invention further includes such multispecific antigen binding molecules for use in immunotherapy, in particular for the treatment of a MMP1+ cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/