The current invention relates to the use of a physiologically acceptable organic and/or inorganic vanadium compound or complex, such as for example bis(maltolato)oxovanadium (BMOV) in the prevention or amelioration of stress-induced metabolic derangement in a subject. More in particular, the invention relates to a physiologically acceptable organic and/or inorganic vanadium compound or complex for use in the amelioration of hyperglycemia in a subject suffering from stress such as elicited by a trauma, wherein the physiologically acceptable organic and/or inorganic vanadium compound or complex is administered to said subject before the trauma is inflicted to the subject. Furthermore, the invention relates to a physiologically acceptable organic and/or inorganic vanadium compound or complex for use in the prevention of hyperglycemia in a subject having a trauma, wherein the physiologically acceptable organic and/or inorganic vanadium compound or complex is administered to said subject before the subject has the trauma. In one embodiment a physiologically acceptable organic and/or inorganic vanadium compound or complex is administered to a human subject 2 to 24 hours before said human subject is subjected to surgery, for the prevention or amelioration of hyperglycemia elicited by a trauma related to the surgery. It is part of the invention that the physiologically acceptable organic and/ or inorganic vanadium compound or complex are a source of vanadyl or vanadate in a patient to whom such compound or complex is administered.La présente invention concerne l'utilisation d'un composé ou d'un complexe de vanadium organique et/ou inorganique physiologiquement acceptable, comme par exemple le bis (maltolato)oxovanadium (BMOV) dans la prévention ou l'amélioration du trouble métabolique induit par le stress chez un sujet. Plus particulièrement, l'invention concerne un composé ou un complexe de vanadium organique et/ou inorganique physiologiquement acceptable destiné à être ut
