Kapil DHINGRA,Brian HIGGINS,Kenneth KOLINSKY,Richard J. LEE,Brian LESTINI,Kathryn PACKMAN,Fei SU
申请号：
US15063227
公开号：
US20160256529A1
申请日:
2016.03.07
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to a combination therapy of propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1H-pyrrolo [2,3-b] pyridine-3-carbonyl-2,4-difluoro-phenyl]-amide}, or a pharmaceutically acceptable salt thereof, and an interferon for treating a patient suffering from a proliferative disorder, in particular a solid tumor, for example, colorectal cancer, melanoma, and thyroid cancer. In particular, the present invention relates to such a therapy wherein the interferon is peginterferon alfa-2a and the disorder is melanoma containing the V600E b-Raf mutation.
