Substituted quinazolines

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专利权人:

Shire LLC

发明人:

Franklin, Richard,Golding, Bernard

申请号：

AU2007327047

公开号：

AU2007327047B2

申请日:

2007.11.19

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

This invention relates to the discovery of 3-and 5-substituted analogues ofthe selective platelet lowering agent anagrelide with reduced potential forcardiovascular side-effects which should lead to improved patient complianceand safety in the treatment of myeloproliferative diseases. More specifically,the present invention relates to certain imidazoquinazoline derivatives whichhave utility as platelet lowering agents in humans. The compounds of the presentinvention function by inhibiting megakaryocytopoeisis and hence the formationof blood platelets.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/