A kind of alternate form and the atomising device with negative pressure structure, are including a container and an atomizer. The container is equipped with an accommodation groove and a negative pressure generates structure, there is a supplement liquid in the accommodation groove and what opening is equipped with a sealing, the atomizer system includes an outer housing and a nebulising element, the shell system is equipped with the squit hole of a mounting groove and the corresponding nebulising element, and one is equipped in the mounting groove and destroys enclosuring structure, the container and the atomizer group connect Hou, and the destruction enclosuring structure system is by the sealing bursting or scratches and flow into the supplement liquid can in the mounting groove and be atomized use by the nebulising element. Generating structure system through the negative pressure and can enable becomes negative pressure state inside the container, avoid droplets from and block the spray nozzle sheet or overflow from the spray nozzle sheet. In addition, the container system is disposable, it is that just what saves carrying.一種替換式且具有負壓結構之霧化裝置，係包括一容器與一霧化器。該容器設有一容置槽與一負壓產生結構，該容置槽內有一補充液體且於開口處設有一封口，該霧化器係包括一外殼體與一霧化元件，該外殼體係設有一安裝槽與對應該霧化元件之噴出孔，且該安裝槽內設有一破壞封口結構，該容器與該霧化器組接後，該破壞封口結構係將該封口頂破或劃破使該補充液體可流入該安裝槽內並由該霧化元件將其霧化使用。透過該負壓產生結構係可令該容器內部成為負壓狀態，避免液滴阻塞該噴孔片或自該噴孔片溢出。此外，該容器係為一次性使用，係便於保存攜帶。
