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Expanding the eukaryotic genetic code
专利权人:
发明人:
Jason W. Chin,T. Ashton Cropp,J. Christopher Anderson,Peter G. Schultz
申请号:
US14574257
公开号:
US09580721B2
申请日:
2014.12.17
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.
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