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נוגדנים נגד 2tie ושימושים שלהם
专利权人:
REGENERON PHARMACEUTICALS INC.
发明人:
申请号:
IL23052914
公开号:
IL230529A
申请日:
2014.01.19
申请国别(地区):
IL
年份:
2017
代理人:
摘要:
The present invention provides antibodies that bind to Tie2 and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human Tie2 and block the interaction between Tie2 and one or more Tie2 ligands such as angiopoietin 1 (Ang1), angiopoietin 2 (Ang2), angiopoietin 3 (Ang3) and/or angiopoietin 4 (Ang4). The antibodies of the invention are useful, inter alia, for the treatment of diseases and disorders associated with one or more Tie2 biological activities including angiogenesis.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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