DØSKELAND, Stein Ove,RONGVED, Pål,HERFINDAL, Lars,LE BORGNE, Marc,VIKTORSSON, Elvar Örn,ÅSTRAND, Ove Alexander Høgmoen
申请号:
GBGB2014/053265
公开号:
WO2015/063516A3
申请日:
2014.11.03
申请国别(地区):
WO
年份:
2015
代理人:
摘要:
The invention provides novel phenazine derivatives of formula I, methods for their preparation and their medical use, in particular as anti-neoplastic agents and anti-infective agents. The invention further relates to novel methods for the preparation of known iodinin and myxin. In formula I R1 to R7 are each independently i.a. hydrogen or alkyl, L is either a direct bond or a linker, and X is a functional group or a biocompatible polymer.Linvention concerne de nouveaux dérivés de phénazine, leurs méthodes de préparation et leur utilisation médicale, en particulier en tant quagents anti-néoplasiques et agents anti-infectieux. Linvention concerne en outre de nouvelles méthodes de préparation diodinine et de myxine.