JUN, HELEN TONI,KEHRY, MARILYN,BOWERS, PETER,KING, DAVID J.,BOBILEV, DMITRI,GHOSH, SRIMOYEE,HUANG, BAOCHUAN,JENKINS, DAVID
申请号:
CA3059468
公开号:
CA3059468A1
申请日:
2018.04.27
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The disclosure provides antibody agents that bind to a Lymphocyte Activation Gene-3 (LAG-3) protein. Particular immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide sequences are explicitly provided. Also provided are related nucleic acids, vectors, compositions, and methods of using anti-LAG-3 antibody agents to treat a disorder or disease that is responsive to LAG-3 inhibition, such as, for example, cancer or an infectious disease.