FORMES CRISTALLINES DE (S) 2 ETHYLBUTYL 2 (((S) (((2R,3S,4R,5R) 5 (4 AMINOPYRROLO[2,1-F] [1,2,4]TRIAZINE-7-YL)-5-CYANO-3,4-DIHYDROXYTETRAHYDROFURAN-2 YL)METHOXY)(PHENOXY) PHOSPHORYL)AMINO)PROPANOATE

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专利权人:

GILEAD SCIENCES; INC.

发明人:

BRAK, KATRIEN,CARRA, ERNEST A.,HEUMANN, LARS V.,LARSON, NATE

申请号：

CA3059777

公开号：

CA3059777A1

申请日:

2018.04.27

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present invention relates to novel salts and crystalline forms of (S)-2-ethylbutyl2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1- f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl) methoxy)(phenoxy)phosphoryl)amino)propanoate (Formula I) for use in treating viral infections. In some embodiments, the viral infection is caused by a virus selected from the group consisting of Arenaviridae, Coronaviridae, Fil oviridae, Fiaviviridae,and Paramyxoviridae.

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