ZEIDAN TAREK A.,REMENAR JULIUS F.,BLUMBERG LAURA COOK
申请号:
NZ59710710
公开号:
NZ597107A
申请日:
2010.06.24
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
597107 Disclosed herein are lactam compounds of Formula I, wherein the variables are defined in the specification, and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety disorder and insomnia. Embodiments of the compounds include the following: (7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-5-dihydroquinolin-1(2H)-yl)methyl 2-(2-(2-methoxyethoxy)ethoxy)acetate, (7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-dihydroquinolin-1(2H)-yl)methyl 4-acetamidobutanoate, and (5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloro-2-oxoindolin-1-yl)methyl palmitate.