The Trustees of The University of Pennsylvania;Novartis AG
发明人:
申请号：
EP14871351.4
公开号：
EP3083964A4
申请日:
2014.12.19
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
Provided are compositions and methods for treating diseases associated with expression of mesothelin. Also provided are a chimeric antigen receptor (CAR) specific to mesothelin, vectors encoding the same, and recombinant T cells comprising the mesothelin CAR. Further provided are methods of administering a genetically modified T cell expressing a CAR that comprises a mesothelin binding domain.
