THE GOVERNMENT OF THE UNITED STATES OF AMERICA; AS REPRESENTED BY THE CRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES; CENTERS FOR DISEASE NTROL AND PREVENTION
发明人:
ANDERSON, LARRY J.,HAYNES, LIA M.,TRIPP, RALPH A.
申请号:
CA2770304
公开号:
CA2770304C
申请日:
2010.08.04
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Immunogenic polypeptides corresponding to one or more RSV G glycoproteins, or analogues thereof, are provided as components of vaccines. The inventive compositions are useful as both a prophylactic and therapeutic for the prevention and treatment of RSV infections and associated pulmonary or other diseases. The inventive immunogens include regions of the RSV G protein, specifically, amino acid residues 164-176 of RSV G A2 protein or analogues thereof. This inventive immunogen is operable alone or in combination with other polypeptides such as the RSV G protein amino acid residues 155-206, or other vaccines such as live RSV vaccines, or inactivated RSV vaccines or immunogenic analogues thereof.