COMPOSITIONS AND METHODS FOR TREATING HEART FAILURE

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专利权人:

Acceleron Pharma Inc.

发明人:

Gang Li,Asya Grinberg,Dianne Sako

申请号：

US16482883

公开号：

US20200087367A1

申请日:

2018.02.05

申请国别(地区):

US

年份:

2020

代理人:

摘要：

In certain aspects, the present disclosure relates to methods of treating, preventing, and reducing the severity or progression of heart failure or one or more complications of heart failure. For example, the disclosure provides various BMP antagonists, such as ActRIIA polypeptides, ActRIIB polypeptides, BMPRII polypeptides, ALKI polypeptides, endoglin polypeptides, BMP 10 propeptide proteins and Fc fusion proteins thereof as well as anti-BMP9 antibodies, for treating, preventing and reducing the severity or progression of heart failure or one or more complications of heart failure.

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中国工程科技知识中心

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http://www.ckcest.cn/home/