In an ophthalmic composition for negative ion SCLs which contains pranoprofen and/or a salt thereof, the present invention purports to provide a technique for suppressing adsorption of the pranoprofen and/or salt thereof to the negative ion SCLs. By causing this negative ion SCL ophthalmic composition containing pranoprofen and/or a salt thereof to contain taurine and/or a salt thereof and setting the pH to 7.7 or less, adsorption of the pranoprofen and/or salt thereof to negative ion SCLs can be effectively suppressed.