Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for processing a CT (Computed Tomography) image are provided. An example method includes accessing an original CT image that is reconstructed from a first set of raw data and includes windmill artifacts, generating a high-frequency image by processing the original CT image, generating a low-frequency image by processing a plurality of thick images reconstructed from a second set of raw data and combining the plurality of processed thick images, the second set of raw data including the first set of raw data and each of the plurality of thick images including substantially no windmill artifacts, generating an intermediate image by synthesizing the high-frequency image and the low-frequency image, and obtaining a target CT image based on the generated intermediate image.