A physiological detection system including a light source module, a photo sensor and a processor is provided. The light source module is configured to provide light to illuminate a skin region. The photo sensor is configured to detect emergent light passing the skin region with at least one signal source parameter and output an image signal. The processor is configured to calculate a confident level according to the image signal to accordingly adjust the at least one signal source parameter.一種生理偵測系統，包含一光源模組、一光感測器以及一處理器。該光源模組用以提供光線照射一皮膚區域。該光感測器用以根據至少一信號源參數偵測經過該皮膚區域之出射光，並輸出一影像信號。該處理器用以根據該影像信號計算一可靠度，並據以調整該至少一信號源參數。
