Tariq Ghayur;Steven Elmore;Andrew Souers;Li Chun Wang;Stuart J. Perper
发明人:
Steven Elmore,Andrew Souers,Li Chun Wang,Tariq Ghayur,Stuart J. Perper
申请号:
US13301898
公开号:
US20120129853A1
申请日:
2011.11.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention pertains to methods of treating systemic lupus erythematosus, lupus nephritis or Sjogren's Syndrome with compounds that selectively inhibit the activity of Bcl-2 anti-apoptotic proteins. Specifically, the current invention is directed to treatment with compounds that selectively inhibit the activity of Bcl-2 proteins, with a lesser affinity for inhibiting the activity of other BCL-2 family proteins, including Bcl-xL.