METHODS AND COMPOSITIONS FOR REDUCING TACTILE DYSFUNCTION AND ANXIETY ASSOCIATED WITH AUTISM SPECTRUM DISORDER, RETT SYNDROME, AND FRAGILE X SYNDROME

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专利权人:

President and Fellows of Harvard College

发明人:

Lauren L. Orefice,David D. Ginty

申请号：

US16308422

公开号：

US20200179374A1

申请日:

2017.06.08

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention features a method of reducing tactile dysfunction or anxiety in a subject diagnosed with Autism Spectrum Disorder, Rett Syndrome, or Fragile X syndrome by administering a GABAA agent having reduced blood brain barrier or by expressing a nucleic acid encoding an exogenous alpha or beta subunit of a GABAA receptor in dorsal root ganglion neurons in the subject using a vector.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/