phosfluconazole derivative, its pharmaceutical composition, its use, its preparation process, intermediate compounds, use, method for improving fluconazole lipophilic character and method for prolonging fluconazole release
JODY FIRMIN MARCELINE VOORSPOELS,YVES RENE JOHANNA PAUL GONNISSEN
申请号：
BRPI1009299
公开号：
BRPI1009299A2
申请日:
2010.03.03
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
The invention relates to a compound of formula (I) and the salts, N-oxides, quaternary amines, and stereoisomers thereof, wherein R1 to R8 are as defined in the claims. The invention further relates to intermediates and methods for the preparation of the compounds of formula (I). The invention also relates to the compounds of formula (I) for use as a medicament, particularly for the prevention or treatment of fungal infections.
