A left atrial appendage closure device system may include an access sheath having a lumen, a delivery sheath slidably disposed within the lumen of the access sheath, and a left atrial appendage closure device slidably disposed within a distal portion of the delivery sheath. The access sheath may include a pre-curved portion adjacent a distal tip of the access sheath. A method of deploying a left atrial appendage closure device may include advancing an access sheath through the superior vena cava and into the right atrium of the heart, advancing a delivery sheath through the access sheath into the left atrium, and deploying the left atrial appendage closure device within the ostium of the left atrial appendage.
