The present disclosure relates to a composition comprising Trigoneoside Ib and Vicenin-1 for treatment and management of Goodpasture’s disease, Glomerulonephritis, Rheumatoid Arthritis, Systemic Lupus Erythematosus and Idiopathic Thrombocytopenia Purpura. The present disclosure also relates to a method of obtaining the said composition from Trigonella foenum-graecum.本發明係關於一種包含葫蘆巴新皂苷Ib及巢菜素-1之組成物,其用於治療及管理古巴士德氏病、腎小球性腎炎、類風濕性關節炎、全身性紅斑狼瘡及特發性血小板減少性紫癜。本發明亦關於一種自葫蘆巴獲得該組成物之方法。