GRANDS ET PETITS ANTIGENES T DE POLYOMAVIRUS DE CELLULES DE MERKEL, PRODUITS DE RECOMBINAISON D'ACIDES NUCLEIQUES ET VACCINS FABRIQUES A PARTIR DE CEUX-CI, ET LEURS PROCEDES D'UTILISATION
Nucleic acid molecules and compositions comprising one or more nucleotide sequences that encode a consensus Merkel Cell Polyomavirus (MCV) T antigen. Immunomodulatory methods and methods of inducing an immune response against MCV are disclosed. Method of treating infection by MCV and methods of treating or preventing Merkel Cell Carcinoma associated with MCV are disclosed. Modified consensus MCV T antigens are disclosed.