ALNYLAM PHARMACEUTICALS INC.;THE UAB RESEARCH FOUNDATION
发明人:
ERBE, DAVID,LIEBOW, ABIGAIL,FITZGERALD, KEVIN,HINKLE, GREGORY,WOOD, KYLE DAVID,HOLMES, ROSS PHILIP,KNIGHT, JOHN
申请号：
CA3069868
公开号：
CA3069868A1
申请日:
2018.07.13
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the LDHA gene, as well as methods of inhibiting epression of LDHA, methods of inhibiting LDHA and HAO1, and methods of treating subjects that would benefit from reduction in expression of LDHA, such as subjects having an oxalate pathway-associated disease, disorder, or condition, using such dsRNA compositions.
