PILGAONKAR PRATIBHA S.,RUSTOMJEE MAHARUKH T.,GANDHI ANILKUMAR S.
申请号：
NZ62830113
公开号：
NZ628301A
申请日:
2013.02.21
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Disclosed herein are compositions comprising a mixture of at least two types of particles wherein a) the first type of particles comprise dabigatran etexilate in the form of the free base or in the form of pharmaceutically acceptable salts, polymorphs, solvates or hydrates thereof； and b) the second type of particles comprise at least one pharmaceutically acceptable organic acid, wherein at least one of the types of particles is coated with a protective coating layer. Also disclosed is the use of the compositions in the reduction of the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation and/or in the prevention of venous thromboembolic events in adult patients who have undergone elective total hip replacement surgery or total knee replacement surgery and processes for the preparation of said compositions.
