A sensor holder for retaining a dental radiation sensing device includes an elongated support member, at least one pair of retention guides attached to the support member, and at least one bite block attached to the support member. The retention guides are capable of holding an associated dental radiation sensing device. The bite block has a leading edge which is first inserted into a mouth of a patient and a trailing edge. The leading edge defining a recess into which structure within the mouth of the patient can seat. At least one of the retention guides may be moveable relative to the other retention guide.