Elisabeth ARKENAU-MARIC,Johannes BARTHOLOMÄUS,Heinrich KUGELMANN
申请号：
US14174876
公开号：
US20140155489A1
申请日:
2014.02.07
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to a process for the production of an abuse-proofed solid dosage form containing at least one active ingredient with potential for abuse and a binder with a breaking strength of ≧500 N, by exposing a mixture comprising the active ingredient and the binder to ultrasound and force.
