Yong-Ji Chung;Young Deug Kim;Jun Young Choi;Eun Mi Kim;Sang Su Song
发明人:
Yong-Ji Chung,Young Deug Kim,Eun Mi Kim,Jun Young Choi,Sang Su Song
申请号：
US12444874
公开号：
US08188049B2
申请日:
2007.10.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to peptides comprising the amino acid sequence represented by the following formula 1 and having the activities of epidermal growth factor and their uses: Cys-Met-Tyr-Ile-Glu-Linker-Arg-Gly-Asp (1) The EGF-mimicking peptides of the present invention possess identical functions or activities to natural-occurring human EGF and are able to promote the generation of autocrine EGF in cells. In addition the peptides of the present invention are much higher stability and skin penetration potency than natural-occurring EGF. Therefore, the composition containing the peptide exhibits excellent treatment and prevention efficacies on diseases or conditions demanding EGF activities, and can be advantageously applied to pharmaceutical compositions, quasi-drugs and cosmetics.
