The present disclosure relates to a multi-span greenhouse having an inflatable and thermal insulation system. The multi-span greenhouse includes a lateral frame, a vertical frame, a top cover, an inflatable and thermal insulation system and a plurality of rotary shafts. The vertical frame is arranged at left and right sides. The lateral frame is arranged above and supported by the vertical frame. The top cover is arranged above the lateral frame. The plurality of rotary shafts are provided at both ends of the lateral frame, and at a top end of the vertical frame. The inflatable and thermal insulation system includes an air compressor, a dust collector, a dehydrator, a dryer, a constant-pressure and air-releasing controller, and a thermal insulation quilt which are communicated with each other in this order through a pipeline. The thermal insulation quilt is provided in the lateral frame and the vertical frame. The multi-span greenhouse having the inflatable and thermal insulation system has a simple structure, reduces manufacture cost and maintenance cost. The multi-span greenhouse has an independent air chamber, which provides a stable air layer with less air convection and ensures thermal insulation property.
