Impurity of lapatinib and salts thereof

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专利权人:

发明人:

申请号：

EP12163219.4

公开号：

EP2489661A1

申请日:

2012.04.04

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention regards an impurity of lapatinib, N-{3-chloro-4-[(2-fluorobynzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl] quinazoline-4-amine compound of formula (I) or a salt thereof:the analytical methods for identifying it and quantifying it in Lapatinib and salts thereof.The invention also regards Lapatinib comprising less than 0.05 percent of this impurity and the relative method of preparation.

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