Protein, use of the combining protein or fragment thereof, method for inducing an immune response in an individual, method for treating a pacemaker, nicleic acid construction, host cell ezpression vector, vaccine, antibody, and, pharmaceutical composition
NEAR DUBLIN;THE POVOST; FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH
发明人:
ANDREJ TAROWSKI (FALECIDO),TIMOTHY FOSTER,JUDY HIGGINS,ELISABET JOSEFSSON,JOAN GEOGHEGAN,ANDREJ TAROWSKI,FOSTER TIMOTHY,HIGGINS JUDY,JOSEFSSO
申请号：
BRPI0906997
公开号：
BRPI0906997A2
申请日:
2009.01.29
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The present invention is directed to improved microbial antigen vaccines, pharmaceutical compositions, immunogenic compositions and antibodies and their use in the treatment of microbial infections, particularly those of bacterial origin, including Staphylococcal origin. Ideally, the present invention is directed to a recombinant staphylococcal MSCRAMM or MSCRAMM-like proteins, or fragment thereof, with reduced binding to its host ligand, for use in therapy.
