A method of producing a positioning guide for an orthodontic bracket is provided. The method includes determining and fixing a position of the orthodontic bracket in relation to a side surface of a corresponding tooth of a setup dental model, wherein the setup dental model has a dentition state of the patient's dental arch after orthodontic treatment; forming a rigid guiding structure with a first part covering the outer surface of each orthodontic bracket and a second part covering the occlusal surface of the corresponding tooth; and forming a flexible linking structure to connect the first part and the second part of the rigid guiding structure to obtain the positioning guide for the respective orthodontic bracket, wherein the rigid guiding structure is inflexible and the flexible linking structure is elastic and retains form.