PROCEDE DE PREPARATION DE COMPOSES D'AMIDE DE DIHYDROINDENE, COMPOSITIONS PHARMACEUTIQUES CONTENANT LES COMPOSES, ET LEUR UTILISATION COMME INHIBITEUR DE PROTEINES KINASES
The invention provides a new kind of dihydroindene amide compounds of generalformula I or theirpharmaceutically acceptable salts or prodrug thereof which can be used asprotein kinase inhibitor.The invention provides a preparation method of the kind of compounds, thepharmaceuticalcompositions containing the compounds, the method for preventing or curing thediseases relatedto the abnormity of activities of protein kinases, especially Abl, Bcr-Abl, c-Kit and PDGFR, using themas protein kinase inhibitor, and their preparation use of drug used forpreventing or curing thediseases related to the abnormity of activities of protein kinases, especiallyAbl, Bcr-Abl, c-Kit andPDGFR.
